20: How a 55-Year-Old Athlete Reversed His Age with AI & Peptides With Tony Medrano Founder & CEO of Longevity.AI

What does it take to build an AI-powered longevity company by using your own body as the lab?

In this episode, Marc Longwith sits down with Tony Medrano, CEO and Co-Founder of LongevityPlan.AI, to break down what peptides actually do, which ones touch the testosterone axis, and how AI and genomics are turning generic protocols into something built for one specific body.

This conversation covers real numbers, real side effects, and the science behind a 55 year old training for his fourth Ironman.

Topics Covered:

• What LongevityPlan.AI's Digital Twin technology does with wearable data, labs, and genetics
• Why wearables like Oura and Whoop give inconsistent readings, and how to use the data anyway
• BPC 157 and TB500 for injury repair, and whether site injection actually matters
• What a peptide actually is, explained through Tony's Lego analogy
• Tesamorelin vs Retatrutide for visceral fat loss and the different mechanisms behind each
• The real side effects at higher GLP-1 doses that don't make it into the marketing
• Why protein intake and resistance training determine whether you keep your muscle on any protocol
• Testosterone, fertility, and the conversation most people are too nervous to have out loud
• Creatine's role in muscle retention, sleep recovery, and reducing dementia risk
• The origin story of BPC 157, tracing back to Pavlov and battlefield medicine
• Where AI, genomics, and biotechnology are headed next, including organ regeneration and implantable health monitoring

Connect with Tony:
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Connect with Marc:
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